An efficient and convenient synthesis of quinazoline derivatives catalyzed by cyanuric chloride in water
نویسندگان
چکیده مقاله:
In this work, an eco-friendly procedure for the preparation of 2,3-dihydroquinazoline-4(1H)-ones was developed by condensation reaction of benzylic and heterocyclic aldehydes with 2-aminobenzamide in the presence of catalytic amounts of cyanuric chloride (2,4,6-trichloro-1,3,5-triazin) as an available and inexpensive organo-catalyst under aqueous media as a green conditions. The new compounds characterized by IR, 1HNMR, 13CNMR, Mass spectrometry, and CHN elemental analysis. Excellent yield, clean reaction media, simple workup and easy purification are advantages of this methodology.
منابع مشابه
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عنوان ژورنال
دوره 6 شماره 4
صفحات 363- 368
تاریخ انتشار 2016-09-01
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